An all-clear for John Roach Center was issued at 10:40 a.m. Tuesday after the university received a bomb threat.
St. Thomas Public Safety issued the alert at 9:48 a.m. Tuesday, evacuated and searched JRC.
All classes in JRC were relocated for the rest of the day. The university said instructors would be sending out relocation information soon. Students could also contact instructors.
Normal operations continue in all other campus locations.
This incident comes four months after a bomb threat was called for McNeely Hall in April, which closed the St. Paul campus for the remainder of that day.
For up-to-date alerts, you can go to the St. Thomas website, Facebook or Twitter accounts.
Emily Haugen, Samantha HoangLong and Justin Amaker contributed to this report.